well then its time to test the rest of the speakers, i would recommend doing this at the radio so any problems with the wiring will also show up, you should use a meter and test for continuity to ground on every speaker wire with the harness unplugged from the radio, it could be any one of the speakers, then if none of the wires shows a short, then test the resistance on each pair of speakers, if one of the either shows a silly low number or an open circuit, then that would be your problem speaker.
i guess it is possible for the radio to be defective as well and just going into protect mode with out reason (very un-common), but you could hook the radio up out side of the car and just hook one speaker up at a time to test the functionality of the radio to make sure.